Tuesday, May 5, 2020

Positive Genetic Engineering Essay Example For Students

Positive Genetic Engineering Essay Genetic Engineering: A leap in to the future or a leap towards destruction?IntroductionScience is a creature that continues to evolve at a much higher rate than the beings that gave it birth. The transformation time from tree-shrew, to ape, to human far exceeds the time from an analytical engine, to a calculator, to a computer. However, science, in the past, has always remained distant. It has allowed for advances in production, transportation, and even entertainment, but never in history has science be able to so deeply affect our lives as genetic engineering will undoubtedly do. With the birth of this new technology, scientific extremists and anti-technologists have risen in arms to block its budding future. Spreading fear by misinterpretation of facts, they promote their hidden agendas in the halls of the United States congress. They fear that it is unsafe; however, genetic engineering is a safe and powerful tool that will yield unprecedented results, specifically in the field of medicine. It will usher in a world where gene defects, bacterial disease, and even aging are a thing of the past. By understanding genetic engineering and its history, discovering its possibilities, and answering the moral and safety questions it brings forth, the blanket of fear covering this remarkable technical miracle can be lifted. The first step to understanding genetic engineering and embracing its possibilities for society is to obtain a rough knowledge base of its history and method. The basis for altering the evolutionary process is dependant on the understanding of how individuals pass on characteristics to their offspring. Genetics achieved its first foothold on the secrets of natures evolutionary process when an Austrian monk named Gregor Mendel developed the first laws of heredity. Using these laws, scientists studied the characteristics of organisms for most of the next one hundred years following Mendels discovery. These early studies concluded that each organism has two sets of character determinants, or genes (Stableford 16). For instance, in regards to eye color, a child could receive one set of genes from his or her father that were encoded one blue, and the other brown. The same child could also receive two brown genes from his or her mother. The conclusion for this inheritance would be the chil d has a three in four chance of having brown eyes, and a one in three chance of having blue eyes (Stableford 16). Genes are transmitted through chromosomes which reside in the nucleus of every living organisms cells. Each chromosome is made up of fine strands of deoxyribonucleic acids, or DNA. The information carried on the DNA determines the cells function within the organism. Sex cells are the only cells that contain a complete DNA map of the organism, therefore, the structure of a DNA molecule or combination of DNA molecules determines the shape, form, and function of the offspring (Lewin 1). DNA discovery is attributed to the research of three scientists, Francis Crick, Maurice Wilkins, and James Dewey Watson in 1951. They were all later accredited with the Nobel Prize in physiology and medicine in 1962 (Lewin 1). The new science of genetic engineering aims to take a dramatic short cut in the slow process of evolution (Stableford 25). In essence, scientists aim to remove one gene from an organisms DNA, and place it into the DNA of another organism. This would create a new DNA strand, full of new encoded instructions; a strand that would have taken Mother Nature millions of years of natural selection to develop. Isolating and removing a desired gene from a DNA strand involves many different tools. DNA can be broken up by exposing it to ultra-highfrequency sound waves, but this is an extremely inaccurate way of isolating a desirable DNA section (Stableford 26). A more accurate way of DNA splicing is the use of restriction enzymes, which are produced by various species of bacteria (Clarke 1). The restriction enzymes cut the DNA strand at a particular location called a nucleotide base, which makes up a DNA molecule. Now that the desired portion of the DNA is cut out, it can be joined to anothe str and of DNA by using enzymes called ligases. The final important step in the creation of a new DNA strand is giving it the ability to self-replicate. This can be accomplished by using special pieces of DNA, called vectors, that permit the generation of multiple copies of a total DNA strand and fusing it to the newly created DNA structure. Another newly developed method, called polymerase chain reaction, allows for faster replication of DNA strands and does not require the use of vectors (Clarke 1). Viewpoint 1The possibilities of genetic engineering are endless. Once the power to control the instructions, given to a single cell, are mastered anything can be accomplished. For example, insulin can be created and grown in large quantities by using an inexpensive gene manipulation method of growing a certain bacteria. This supply of insulin is also not dependant on the supply of pancreatic tissue from animals. Recombinant factor VIII, the blood clotting agent missing in people suffering from hemophilia, can also be created by genetic engineering. Virtually all people who were treated with factor VIII before 1985 acquired HIV, and later AIDS. Being completely pure, the bioengineered version of factor VIII eliminates any possibility of viral infection. Other uses of genetic engineering include creating disease resistant crops, formulating milk from cows already containing pharmaceutical compounds, generating vaccines, and altering livestock traits (Clarke 1). In the not so distant future, genetic engineering will become a principal player in fighting genetic, bacterial, and viral disease, along with controlling aging, and providing replaceable parts for humans. Medicine has seen many new innovations in its history. The discovery of anesthetics permitted the birth of modern surgery, while the production of antibiotics in the 1920s minimized the threat from diseases such as pneumonia, tuberculosis and cholera. The creation of serums which build up the bodies immune sys tem to specific infections, before being laid low with them, has also enhanced modern medicine greatly (Stableford 59). All of these discoveries will fall under the broad shadow of genetic engineering when it reaches its apex in the medical community. Canada's Copyright Law EssayThe evolution of man can be broken up into three basic stages. The first, lasting millions of years, slowly shaped human nature from Homo erectus to Home sapiens. Natural selection provided the means for countless random mutations resulting in the appearance of such human characteristics as hands and feet. The second stage, after the full development of the human body and mind, saw humans moving from wild foragers to an agriculture based society. Natural selection received a helping hand as man took advantage of random mutations in nature and bred more productive species of plants and animals. The most bountiful wheats were collected and re-planted, and the fastest horses were bred with equally faster horses. Even in our recent history the strongest black male slaves were mated with the hardest working female slaves. The third stage, still developing today, will not require the chance acquisition of super-mutations in nature. Man will be able to create s uch super-species without the strict limitations imposed by natural selection. By examining the natural slope of this evolution, the third stage is a natural and inevitable plateau that man will achieve (Stableford 8). This omniscient control of our world may seem completely foreign, but the thought of the Egyptians erecting vast pyramids would have seem strange to Homo erectus as well. ConclusionMany claim genetic engineering will cause unseen disasters spiraling our world into chaotic darkness. However, few realize that many safety nets regarding bioengineering are already in effect. The Recombinant DNA Advisory Committee (RAC) was formed under the National Institute of Health to provide guidelines for research on engineered bacteria for industrial use. The RAC has also set very restrictive guidelines requiring Federal approval if research involves pathogenicity (the rare ability of a microbe to cause disease) (Davis, Roche 69). It is well established that most natural bacteria do not cause disease. After many years of experimentation, microbiologists have demonstrated that they can engineer bacteria that are idence of regeneration is all around and the science of genetic engineering is slowly mastering its techniques. Regeneration in mammals is essentially a kind of controlled cancer, called a blastema. The cancer is deliberately formed at the regeneration site and then converted into a structure just as safe as their natural counterparts (Davis and Rouche 70). In fact the RAC reports that there has not been a single case of illness or harm caused by recombinant bacteria, and they now are used safely in high school experiments (Davis and Rouche 69). Scientists have also devised other methods of preventing bacteria from escaping their labs, such as modifying the bacteria so that it will die if it is removed from the laboratory environment. This creates a shield of complete safety for the outside world. It i s also thought that if such bacteria were to escape it would act like smallpox or anthrax and ravage the land. However, laboratory-created organisms are not as competitive as pathogens. Davis and Roche sum it up in extremely laymens terms, no matter how much Frostban you dump on a field, its not going to spread (70). In fact Frostbran, developed by Steven Lindow at the University of California, Berkeley, was sprayed on a test field in 1987 and was proven by a RAC committee to be completely harmless (Thompson 104). Fear of the unknown has slowed the progress of many scientific discoveries in the past. The thought of man flying or stepping on the moon did not come easy to the average citizens of the world. But the fact remains, they were accepted and are now an everyday occurrence in our lives. Genetic engineering is in its period of fear and misunderstandifng, but like every great discovery in history, it will enjoy its time of realization and come into full use in society. The world is on the brink of the most exciting step into human evolution ever, and through knowledge and exploration, should welcome it and its possibilities with open arms. BibliographyBioethics: an Introduction. N. d. Online posting. Internet. 2 Dec. 1997. Clarke, Bryan C. Genetic Engineering. Microsoft (r) Encarta. Microsoft Corporation, Funk ; Wagnalls Corporation, 1994. Davis, Bernard, and Lissa Roche. Sorcerers Apprentice or Handmaiden to Humanity. USA TODAY: The Magazine of the American Scene 118 Nov 1989: 68-70. Lewin, Seymour Z. Nucleic Acids. Microsoft (r) Encarta. Microsoft Corporation, Funk Wagnalls CorporationShapiro, Harold T. Ethical and Policy Issues of Human Cloning Journal Group: Sci/tech 11 Jul. 1997. 195-196. CD-ROM. UMI-Proquest. Snell, Marilyn Berlin Bioprospecting or Biopiracy? Utne Reader March/April 1996. 82-93. UTNE READER 1996. SIRS, 1996. Stableford, Brian. Future Man. New York: Crown Publishers, Inc., 1984. Thompson, Dick. The Most Hated Man in Science. Time 23 Dec 4 1989: 102-104

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